insulin receptor

基本解释

In order for a cell to respond directly to insulin it must display an insulin receptor on its surface.
为了使一个细胞能够直接对胰岛素做出反应，因此在它表面必须有一个胰岛素受体。
To confirm this, the researchers gave the insulin receptor-deficient mice osteocalcin, which improved their metabolic abnormalities.
为了验证这一说法，研究者们给这些缺少胰岛素受体的实验小鼠们注入了骨钙蛋白，而这一举动确实改善了它们的代谢反常现象。
International Diabetes: Doctor do you think that the modulation of Insulin receptor signaling is the major method to improvement insulin resistance?
国际糖尿病：教授，您认为调节胰岛素受体信号是改善胰岛素抵抗的主要方法吗？
www.idiabetes.com.cn

It gets enhanced because when insulin binds to the insulin receptor, it activates the receptor.
这种增强效应来自于,胰岛素与胰岛素受体结合后,就激活了该受体
耶鲁公开课 - 生物医学工程探索课程节选
Insulin, the ligand binds to its receptor, creates a change through a kinase activity that's exposed, which leads to other biochemical changes, which leads to a change in cell behavior - in this case the cell behavior is that more glucose transporters are brought to the membrane and more glucose can enter the cell.
胰岛素,一种能够与受体结合的配体,通过其暴露出的激酶活性引起的变化,导致了其它后续生化变化的发生,进而使细胞行为发生改变,这个例子中的细胞行为就是,更多的糖载体被带到细胞膜表面,这样更多的糖分子进入到细胞内部
耶鲁公开课 - 生物医学工程探索课程节选

Sometimes it is a normal gene that directs the production of a hormone, such as insulin, or of the cell machinery which that hormone stimulates, such as the insulin receptor.
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We will routinely turn off genes that promote disease and aging such as the fat insulin receptor gene that tells the fat cells to hold onto excess fat.
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