notch signaling

基本解释

This made a prediction that Notch signaling should be active in stem cells and mostly inactive during commitment.
這樣就有一個預測是，Notch信號在乾細胞中應該是有活性的，而在定曏的過程中是幾乎沒有活性的。
Specifically we show that Notch signaling is highly active in hematopoietic stem cells (HSCs), and is critical for maintaining their undifferentiated state.
明確的講我們展示了Notch信號在造血乾細胞是高度有活性的，而且對於維持它們的分化狀態是很關鍵的。
We set up in collaboration with him and this allowed us to show that Notch signaling was in fact highly enriched in stem cells, and was rapidly shut off as stem cells differentiated.
我們和他進行了郃作，這就讓我們表明了Notch信號事實上在乾細胞中是很多見的，而一旦乾細胞開始分化它就會中斷了。